The early stages of prostate cancer are typically androgen dependent—meaning that they need male hormones to grow. But, cholesterol is needed to produce the sex hormones that fuel the growth of certain cancers.

The authors say that by affecting cholesterol, red yeast rice can reduce androgen production in prostate cancer cells. This may not only halt cancer cell growth, but also help prevent early, androgen-dependent prostate cancers from progressing to the more advanced and harder-to-treat androgen-independent cancers.

“Our current study proves that red yeast rice is protective against androgen-independent, as well as androgen-dependent prostate cancers,” says lead study author, PhD, an assistant professor at the School of Exercise and Nutritional Sciences at San Diego State University. “Therefore, the use of red yeast rice would be a novel approach to treat advanced androgen-independent prostate cancer in order to reduce overall prostate cancer mortality”(2).

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1- Hong MY, Seeram NP, Zhang Y, Heber D. Chinese red yeast rice versus lovastatin effects on prostate cancer cells with and without androgen receptor overexpression. Journal of Medicinal Food. 2008;11:657-666.

2-Hong, Mee Young, et al. Anticancer effects of Chinese red yeast rice versus monacolin K alone on colon cancer cells. Journal of Nutritional Biochemistry. 2008:19:448-458

Graaf MR, et al. The risk of cancer in users of statins. Journal of Clinical Oncology, 2004. 22;2388-2394.